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This methyl group transfer is critical for epigenetic regulation, influencing gene expression patterns, chromatin structure, and signal transduction pathways
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In a Multicenter Italian Trial in Ovarian cancer (MITO-4), 22 out of 60 neuropathic patients (37%) treated with carboplatin and paclitaxel reported complete recovery in the first 2 months after the end of the chemotherapy (Pignata et al., 2006)
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