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Individuals with known copper allergies or sensitivities Those with active skin infections or open wounds on the treatment area Pregnant or breastfeeding individuals, due to limited safety data Patients using other active skincare ingredients who want to avoid interactions Anyone with a history of severe skin reactions to new products This is why a personalized primary care visit matters before starting any new regimen

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[74] is also important since these investigators demonstrated that a high-fat diet induced skeletal muscle OxS (and insulin resistance) by promoting mitochondrial H 2 O 2 emission