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249,250 In vivo studies confirm mitochondrial dysfunction in high-fat diet mice, which develop neuropathy marked by reduced nerve conduction velocities and decreased IENFD
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Treatments such as the intragastric balloon (a temporary inflatable balloon placed in the stomach) and endoscopic sleeve gastroplasty (suturing the stomach into a narrower tube without removing tissue) offer less invasive options, though weight loss is generally less than with surgery
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