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e , Quantification of NETs formation in human primary neutrophils from healthy donors (HD, n = 8) treated with PMA (5 nM) for 4 h, in the presence or absence of caspase-3 inhibitors QVD (10 µM), Z-VAD (30 µM) or Emricasan (10 µM) ( n = 8)

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AMPK also inhibits lipid biosynthesis by suppressing transcription factor sterol regulatory element-binding protein 1 (SREBP1) and promoting the action of peroxisome proliferator-activated receptor alpha (PPARα), a nuclear receptor that acts to enhance both mitochondrial and peroxisomal FA β-oxidation 23