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Pathohistological examinations of both acute and chronic toxicity revealed that L-NAME caused severe tissue damage (myocardial and hepatic cell necrosis, and necrosis of the lymphoid cells in the spleen) while L-arginine provoked predominantly congestion, edema and hemorrhages in all organs
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[DOI] [PMC free article] [PubMed] [Google Scholar] Dupasquier M., Stoitzner P., van Oudenaren A., Romani N., Leenen P.J.M
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