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Likewise, the viral ICP27, an IE protein has been reported to block caspase 3-associated apoptosis, as evidenced with a mutant of HSV-1 that has ICP27 deleted (Aubert and Blaho, 2005)
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The transmembrane iron chelator desferridone (DFP) can improve the overexpression of HO-1 in astrocytes and lead to iron deposition in the striatum (Song et al., 2017
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