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Furthermore, we found that the expression of the p-NF-κB p65 protein was upregulated in peroxynitrite-exposed SGNs compared with the untreated controls, and the pretreatment with ebselen significantly reduced it while the lack of GPX1 increased it (Figure 8C)
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Phase I changes the estrogen into a different form, and Phase II—where glutathione is a star player—attaches a molecule to the estrogen to make it water-soluble so it can be flushed out
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